The Journal of Oral Laser Applications
J Oral Laser Applications 10 (2010), No. 4     14. June 2011
J Oral Laser Applications 6 (2006), No. 2  (05.06.2006)

Page 123-131

Combination Therapy of Intrabony Periodontal Defects Using an Er:YAG Laser and Enamel Matrix Protein Derivative: A Case Series
Schwarz, Frank/Sculean, Anton/Bieling, Katrin/Becker, Jürgen/Romanos, George E.
Purpose: The aim of the present series of case reports was to evaluate the combination therapy of intrabony periodontal defects using an Er:YAG laser (ERL) and enamel matrix protein derivative (EMD).
Materials and Methods: Fifteen patients with chronic periodontitis, each of whom displayed one intrabony defect, were randomly treated with access flap surgery and root surface/defect debridement using ERL (16.5 J/cm2) followed by the application of EMD. The following clinical parameters were recorded at baseline and at 6 months: plaque index (PI), bleeding on probing (BOP), probing pocket depth (PD), gingival recession (GR), and clinical attachment level (CAL).
Results: Healing was uneventful in all patients. At 6 months after therapy, the sites treated with ERL and EMD showed a mean PD reduction from 8.5 ± 1.1 mm to 4.7 ± 0.8 mm and a mean CAL change from 10.5 ± 1.4 mm to 7.6 ± 1.4 mm (p < 0.001).
Conclusion: Within the limits of this case series, it may be concluded that the combination of ERL and EMD may improve clinical healing of intrabony periodontal defects over a period of 6 months.

Keywords: case series, enamel proteins, intrabony defects, lasers, periodontal regeneration, therapeutic use