J Oral Laser Applications 5 (2005), No. 4 (29.11.2005)
A Histopathological Study of Wound Healing in Rabbit Oral Mucosa After Incisions Made with Electrocautery or CO2 Laser
Fisekcioglu, Erdogan/Dumlu, Asim/Ozdemir, Nilgun
Purpose: The aim of this preliminary study involving 6 rabbits was to histologically compare the wound healing of incisions in the oral mucosa made by a CO2 laser focus probe, a CO2 laser nonfocus probe, and electrocautery.
Materials and Methods: Incisions 5 mm long and 1 mm deep were made in the buccal mucosa of 6 male rabbits weighing between 3 to 4.5 kg. Punch biopsies, 5 mm in diameter, were obtained immediately postoperatively (day 0) and on the 14th day. The presence or severity of the following histological parameters was evaluated: hyperemia, ulcer, edema, thermal depth, acanthosis, parakeratosis, fibrosis, erosion.
Results: Histological findings demonstrated that the performance of the focus laser was similar to electrocautery. However, the performance of nonfocus laser was generally inferior to both as it was the only technique to produce ulceration on the 14th day.
Conclusion: The results of this preliminary study confirm that further studies must be done on CO2 lasers for oral mucosa surgery.
Keywords: CO2 laser, electrocautery, wound healing